Defactinib
| CAS No. | 1073154-85-4 | Cat. No. | BCP11299 |
| Name | Defactinib | ||
| Synonyms | VS-6063;VS6063;VS 6063;PF04554878; PF-04554878; PF 04554878; PF4554878; PF-4554878; PF4554878; | ||
| Formula | C20H21F3N8O3S | M. Wt | 510.14 |
| Description | Defactinib, also known as VS-6063 and PF-04554878, is an orally bioavailable, small-molecule focal adhesion kinase (FAK) inhibitor with potential antiangiogenic and antineoplastic activities. FAK inhibitor PF-04554878 inhibits FAK, which may prevent the integrin-mediated activation of several downstream signal transduction pathways, including ERK, JNK/MAPK and PI3K/Akt, thus inhibiting tumor cell migration, proliferation and survival. | ||
| Related Products | 1345713-71-4（Defactinib） 1073160-26-5（Defactinib hydrochloride） | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | FAK | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.