Dorzagliatin

CAS No.	1191995-00-2	Cat. No.	BCP20539
Name	Dorzagliatin
Synonyms	Sinogliatin; HMS 5552; HMS-5552; HMS5552; RO5305552; RO-5305552; RO 5305552;
Formula	C22H27ClN4O5	M. Wt	462.93

Description	Dorzagliatin, also known as HMS 5552, RO5305552 and sinogliatin, is a novel Dual-Acting Glucokinase Activator, which Improves Glycaemic Control and Pancreatic β-Cell Function in Patients With Type 2 Diabetes. By addressing the defect of the glucose sensor function of glucokinase, dorzagliatin has the potential to restore the impaired glucose homeostasis state of people with type 2 diabetes and serve as a first-line standard-of-care therapy for the treatment of the disease, or as a cornerstone therapy when taken in combination with currently approved anti-diabetes drugs.
Pathways	Protease/Metabolic Enzyme
Targets	Glucokinase

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