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CAS No. | 1191995-00-2 | Cat. No. | BCP20539 |
Name | Dorzagliatin | ||
Synonyms | Sinogliatin; HMS 5552; HMS-5552; HMS5552; RO5305552; RO-5305552; RO 5305552; | ||
SMILES | O=C(NC1=NN(C[C@@H](O)CO)C=C1)[C@@H](N2CC(OC(C=CC=C3)=C3Cl)=CC2=O)CC(C)C | ||
Chemical Name | |||
Formula | C22H27ClN4O5 | M. Wt | 462.93 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Dorzagliatin, also known as HMS 5552, RO5305552 and sinogliatin, is a novel Dual-Acting Glucokinase Activator, which Improves Glycaemic Control and Pancreatic β-Cell Function in Patients With Type 2 Diabetes. By addressing the defect of the glucose sensor function of glucokinase, dorzagliatin has the potential to restore the impaired glucose homeostasis state of people with type 2 diabetes and serve as a first-line standard-of-care therapy for the treatment of the disease, or as a cornerstone therapy when taken in combination with currently approved anti-diabetes drugs. |
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