GDC0276
| CAS No. | 1494581-70-2 | Cat. No. | BCP25410 |
| Name | GDC0276 | ||
| Synonyms | GDC-0276; GDC 0276; RG7893; RG-7893; RG 7893; | ||
| Formula | C24H31FN2O4S | M. Wt | 462.58 |
| Description | GDC-0276 is a potent, selective, reversible and orally active NaV1.7 inhibitor with an IC50 value of 0.4 nM. GDC-0276 is well tolerated and exhibits a good pharmacokinetic profile. GDC-0276 has the potential for the treatment of pain and to address shortcomings of existing pain medications, such as addiction and off-target side effects. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | Sodium Channel | ||
Structure
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