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CAS No. | 1494581-70-2 | Cat. No. | BCP25410 |
Name | GDC0276 | ||
Synonyms | GDC-0276; GDC 0276; RG7893; RG-7893; RG 7893; | ||
SMILES | C1CN(C1)S(=O)(=O)NC(=O)C2=C(C=C(C(=C2)C3CC3)OCC45CC6CC(C4)CC(C6)C5)F | ||
Chemical Name | |||
Formula | C24H31FN2O4S | M. Wt | 462.58 |
Purity | 98% | Storage | Store at 4-8°C |
Description | GDC-0276 is a potent, selective, reversible and orally active NaV1.7 inhibitor with an IC50 value of 0.4 nM. GDC-0276 is well tolerated and exhibits a good pharmacokinetic profile. GDC-0276 has the potential for the treatment of pain and to address shortcomings of existing pain medications, such as addiction and off-target side effects. |
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