R-GNE-140

Chemical Properties

CAS No.	2003234-63-5	Cat. No.	BCP20732
Name	R-GNE-140
Synonyms	GNE-140;(R)-GNE-140; GNE 140; GNE140;
Formula	C25H23ClN2O3S2	M. Wt	499.04

Biological Activity

Description	(R)-GNE-140 is a potent lactate dehydrogenase A (LDHA) inhibitor, with IC50s of 3 nM and 5 nM for LDHA and LDHB, respectively；(R)-GNE-140 is 18-fold more potent than S enantiomer. IC50 & Target: IC50: 3 nM (LDHA), 5 nM (LDHB)

Description

(R)-GNE-140 is a potent lactate dehydrogenase A (LDHA) inhibitor, with IC50s of 3 nM and 5 nM for LDHA and LDHB, respectively；(R)-GNE-140 is 18-fold more potent than S enantiomer. IC50 & Target: IC50: 3 nM (LDHA), 5 nM (LDHB)

Structure

Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.

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