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R-GNE-140 Chemical Structure

R-GNE-140

Data Sheet For research use only. Not for human use.
Cat. No. :BCP20732CAS No. :2003234-63-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2003234-63-5 Cat. No. BCP20732
Name R-GNE-140
Synonyms GNE-140;(R)-GNE-140; GNE 140; GNE140;
SMILES C1COCCN1C2=CC=C(C=C2)C3(CC(=C(C(=O)N3)SC4=CC=CC=C4Cl)O)C5=CSC=C5
Chemical Name
Formula C25H23ClN2O3S2 M. Wt 499.04
Purity 98% Storage Store at 4-8°C
Description (R)-GNE-140 is a potent lactate dehydrogenase A (LDHA) inhibitor, with IC50s of 3 nM and 5 nM for LDHA and LDHB, respectively;(R)-GNE-140 is 18-fold more potent than S enantiomer. IC50 & Target: IC50: 3 nM (LDHA), 5 nM (LDHB)
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