DOI hydrochloride
| CAS No. | 42203-78-1 | Cat. No. | BCP25643 |
| Name | DOI hydrochloride | ||
| Synonyms | DOI HCl; | ||
| Formula | C11H17ClINO2 | M. Wt | 357.61 |
| Description | DOI hydrochloride is a brain penetrant, mixed 5-HT2A/5-HT2C receptor agonist (Ki values are 0.7, 2.4 and 20 nM for 5-HT2A, 5-HT2C and 5-HT2B receptors respectively). Reduces rapid eye movement (REM) and slow wave sleep and increases waking in the rat. Hallucinogenic agent. Acts via 5-HT2A receptors to inhibit the inflammatory effects of tumor necrosis factor (TNF)-α. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | 5 HT Receptor/Serotonin Receptor PDGFR | ||
Structure
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