DOI hydrochloride New
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CAS No. | 42203-78-1 | Cat. No. | BCP25643 |
Name | DOI hydrochloride | ||
Synonyms | DOI HCl; | ||
SMILES | CC(CC1=CC(=C(C=C1OC)I)OC)N.Cl | ||
Chemical Name | |||
Formula | C11H17ClINO2 | M. Wt | 357.61 |
Purity | 98% | Storage | Store at 4-8°C |
Description | DOI hydrochloride is a brain penetrant, mixed 5-HT2A/5-HT2C receptor agonist (Ki values are 0.7, 2.4 and 20 nM for 5-HT2A, 5-HT2C and 5-HT2B receptors respectively). Reduces rapid eye movement (REM) and slow wave sleep and increases waking in the rat. Hallucinogenic agent. Acts via 5-HT2A receptors to inhibit the inflammatory effects of tumor necrosis factor (TNF)-α. |
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