PT2399
| CAS No. | 1672662-14-4 | Cat. No. | BCP25901 |
| Name | PT2399 | ||
| Synonyms | PT-2399; PT 2399; | ||
| Formula | C17H10F5NO4S | M. Wt | 419.32 |
| Description | PT2399 is a first-in-class, orally available, small molecule inhibitor of HIF-2 that selectively disrupts the heterodimerization of HIF-2α with HIF-1β. Preclinical and clinical data indicate that PT2399 is effective in blocking cancer cell growth, proliferation, and tumor angiogenesis characteristic in ccRCC. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | HIF | ||
Structure
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