KN-93 hydrochloride
| CAS No. | 1956426-56-4 | Cat. No. | BCP25921 |
| Name | KN-93 hydrochloride | ||
| Synonyms | KN-93 (HCI); KN-93 HCI; KN-93-HCI; KN93 (HCI); KN93 Hydrochloride; KN 93 Hydrochloride; KN-93(Hydrochloride); | ||
| Formula | C26H30Cl2N2O4S | M. Wt | 537.49 |
| Description | KN-93 hydrochloride is a novel membrane-permeant synthetic inhibitor of purified neuronal CaMK-II, with Ki of 370 nM.KN-93 is an inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMK-II). It inhibits fibroblast CaMK-II activity and cell growth in a dose-dependent manner, reversibly arrests cells in G1 and induces apoptosis. | ||
| Pathways | Neuro Signaling Pathway | ||
| Targets | CaMK | ||
Structure
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