KN-93 hydrochloride
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CAS No. | 1956426-56-4 | Cat. No. | BCP25921 |
Name | KN-93 hydrochloride | ||
Synonyms | KN-93 (HCI); KN-93 HCI; KN-93-HCI; KN93 (HCI); KN93 Hydrochloride; KN 93 Hydrochloride; KN-93(Hydrochloride); | ||
SMILES | |||
Chemical Name | |||
Formula | C26H30Cl2N2O4S | M. Wt | 537.49 |
Purity | 98% | Storage | Store at 4-8°C |
Description | KN-93 hydrochloride is a novel membrane-permeant synthetic inhibitor of purified neuronal CaMK-II, with Ki of 370 nM.KN-93 is an inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMK-II). It inhibits fibroblast CaMK-II activity and cell growth in a dose-dependent manner, reversibly arrests cells in G1 and induces apoptosis. |
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