K67

  • Chemical Properties
CAS No. 2046250-48-8 Cat. No. BCP26006
Name K67
Synonyms K 67; K-67;
Formula C29H30N2O7S2 M. Wt 582.68
  • Biological Activity
Description K67 is a specific inhibitor against the interaction between KEAP1 DC domain and S349-phosphorylated KIR of p62/SQSTM1, K67 effectively inhibits the proliferation of HCC cultures with high cellular p62 S351-phosphorylation by restoring KEAP1-driven NRF2 ubiquitination and degradation.
Pathways NFκB 
Targets Keap1 Nrf2 

Structure

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