K67
CAS No. | 2046250-48-8 | Cat. No. | BCP26006 |
Name | K67 | ||
Synonyms | K 67; K-67; | ||
Formula | C29H30N2O7S2 | M. Wt | 582.68 |
Description | K67 is a specific inhibitor against the interaction between KEAP1 DC domain and S349-phosphorylated KIR of p62/SQSTM1, K67 effectively inhibits the proliferation of HCC cultures with high cellular p62 S351-phosphorylation by restoring KEAP1-driven NRF2 ubiquitination and degradation. | ||
Pathways | NFκB | ||
Targets | Keap1 Nrf2 |
Structure
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