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CAS No. | 2046250-48-8 | Cat. No. | BCP26006 |
Name | K67 | ||
Synonyms | K 67; K-67; | ||
SMILES | CC(CC1=CC(NS(C2=CC=C(OCC)C=C2)(=O)=O)=C3C=CC=CC3=C1NS(C4=CC=C(OCC)C=C4)(=O)=O)=O | ||
Chemical Name | |||
Formula | C29H30N2O7S2 | M. Wt | 582.68 |
Purity | 98% | Storage | Store at 4-8°C |
Description | K67 is a specific inhibitor against the interaction between KEAP1 DC domain and S349-phosphorylated KIR of p62/SQSTM1, K67 effectively inhibits the proliferation of HCC cultures with high cellular p62 S351-phosphorylation by restoring KEAP1-driven NRF2 ubiquitination and degradation. |
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