Capromorelin methanesulfonate
| CAS No. | 193273-67-5 | Cat. No. | BCP26264 |
| Name | Capromorelin methanesulfonate | ||
| Synonyms | CP 424391 methanesulfonate;CP424391 methanesulfonate;CP-424391 methanesulfonate; | ||
| Formula | C29H39N5O7S | M. Wt | 601.71 |
| Description | Capromorelin, also known as CP-424,391, is a growth hormone secretagogue and ghrelin mimetic ( hGHS-R1a K(i)=7 nM, rat pituicyte EC(50)=3 nM). Initial studies have shown the drug to directly raise insulin growth factor 1 (IGF-1) and growth hormone levels. Capromorelin showed enhanced intestinal absorption in rodent models and exhibited superior pharmacokinetic properties, including high bioavailabilities in two animal species [F(rat)=65%, F(dog)=44%]. This short-duration GHS was orally active in canine models and was selected as a development candidate for the treatment of musculoskeletal frailty in elderly adults. | ||
| Pathways | GPCR/G Protein | ||
| Targets | GHSR | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.