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Capromorelin methanesulfonate Chemical Structure

Capromorelin methanesulfonate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP26264CAS No. :193273-67-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 193273-67-5 Cat. No. BCP26264
Name Capromorelin methanesulfonate
Synonyms CP 424391 methanesulfonate;CP424391 methanesulfonate;CP-424391 methanesulfonate;
SMILES
Chemical Name
Formula C29H39N5O7S M. Wt 601.71
Purity 98% Storage Store at 4-8°C
Description Capromorelin, also known as CP-424,391, is a growth hormone secretagogue and ghrelin mimetic ( hGHS-R1a K(i)=7 nM, rat pituicyte EC(50)=3 nM). Initial studies have shown the drug to directly raise insulin growth factor 1 (IGF-1) and growth hormone levels. Capromorelin showed enhanced intestinal absorption in rodent models and exhibited superior pharmacokinetic properties, including high bioavailabilities in two animal species [F(rat)=65%, F(dog)=44%]. This short-duration GHS was orally active in canine models and was selected as a development candidate for the treatment of musculoskeletal frailty in elderly adults.
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