Elubrixin hydrochloride
| CAS No. | 688763-65-7 | Cat. No. | BCP23554 |
| Name | Elubrixin hydrochloride | ||
| Synonyms | Elubrixin HCl;SB-656933; SB 656933; SB656933; SB-656933-AAF; SB-656933 AAF; SB-656933AAF; | ||
| Formula | C17H18Cl3FN4O4S | M. Wt | 499.77 |
| Description | Elubrixin is a interleukin 8 inhibitor and CXCR2 selective antagonist, which is potentially useful for Inflammatory bowel disease therapies. Elubrixin inhibits ex vivo neutrophil activation and ozone-induced airway inflammation in humans. demonstrates dose-dependent effects on neutrophil activation and recruitment within a well-tolerated dose range. SB-656933 may be an effective agent in neutrophil-predominant diseases. | ||
| Pathways | GPCR/G Protein | ||
| Targets | CXCR | ||
Structure
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