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CAS No. | 688763-65-7 | Cat. No. | BCP23554 |
Name | Elubrixin hydrochloride | ||
Synonyms | Elubrixin HCl;SB-656933; SB 656933; SB656933; SB-656933-AAF; SB-656933 AAF; SB-656933AAF; | ||
SMILES | C1CN(CCN1)S(=O)(=O)C2=C(C=CC(=C2O)NC(=O)NC3=C(C(=CC=C3)F)Cl)Cl.Cl | ||
Chemical Name | |||
Formula | C17H18Cl3FN4O4S | M. Wt | 499.77 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Elubrixin is a interleukin 8 inhibitor and CXCR2 selective antagonist, which is potentially useful for Inflammatory bowel disease therapies. Elubrixin inhibits ex vivo neutrophil activation and ozone-induced airway inflammation in humans. demonstrates dose-dependent effects on neutrophil activation and recruitment within a well-tolerated dose range. SB-656933 may be an effective agent in neutrophil-predominant diseases. |
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