LX-2343

  • Chemical Properties
CAS No. 333745-53-2 Cat. No. BCP28952
Name LX-2343
Synonyms LX 2343; LX-2343;
Formula C22H19ClN2O6S M. Wt 474.91
  • Biological Activity
Description LX-2343 is a neuroprotective agent for the treatment of Alzheimer's disease. LX2343 ameliorates cognitive dysfunction in APP/PS1 transgenic mice via both Aβ production inhibition and clearance promotion, which highlights the potential of LX2343 in the treatment of AD. LX2343 ameliorates the cognitive dysfunction in the AD model rats by suppressing OS-induced neuronal apoptosis and tauopathy, thus highlighting the potential of LX2343 for the treatment of AD.
Pathways Neuro Signaling Pathway Others Pathway PI3K/Akt/mTOR 
Targets Beta secretase Autophagy PI3K 

Structure

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