LX-2343
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CAS No. | 333745-53-2 | Cat. No. | BCP28952 |
Name | LX-2343 | ||
Synonyms | LX 2343; LX-2343; | ||
SMILES | COC1=C(C=C(C=C1)Cl)N(CC(=O)NC2=CC3=C(C=C2)OCO3)S(=O)(=O)C4=CC=CC=C4 | ||
Chemical Name | |||
Formula | C22H19ClN2O6S | M. Wt | 474.91 |
Purity | 98% | Storage | Store at 4-8°C |
Description | LX-2343 is a neuroprotective agent for the treatment of Alzheimer's disease. LX2343 ameliorates cognitive dysfunction in APP/PS1 transgenic mice via both Aβ production inhibition and clearance promotion, which highlights the potential of LX2343 in the treatment of AD. LX2343 ameliorates the cognitive dysfunction in the AD model rats by suppressing OS-induced neuronal apoptosis and tauopathy, thus highlighting the potential of LX2343 for the treatment of AD. |
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