ML-327

  • Chemical Properties
CAS No. 1883510-31-3 Cat. No. BCP29132
Name ML-327
Synonyms ML 327; ML327;
Formula C19H18N4O4 M. Wt 366.37
  • Biological Activity
Description ML327 is a blocker of MYC. ML327 mediated transcriptional de-repression of E-cadherin and inhibition of epithelial-to-mesenchymal transition. ML327 induces apoptosis and sensitizes Ewing sarcoma cells to TNF-related apoptosis-inducing ligand. ML327 blocks MYC expression and tumor formation in neuroblastoma.
Pathways Apoptosis Pathway 
Targets c Myc 

Structure

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