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ML-327
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CAS No. | 1883510-31-3 | Cat. No. | BCP29132 |
Name | ML-327 | ||
Synonyms | ML 327; ML327; | ||
SMILES | O=C(C1=CC=CNC1=O)NCCCNC(C2=NOC(C3=CC=CC=C3)=C2)=O | ||
Chemical Name | |||
Formula | C19H18N4O4 | M. Wt | 366.37 |
Purity | 98% | Storage | Store at 4-8°C |
Description | ML327 is a blocker of MYC. ML327 mediated transcriptional de-repression of E-cadherin and inhibition of epithelial-to-mesenchymal transition. ML327 induces apoptosis and sensitizes Ewing sarcoma cells to TNF-related apoptosis-inducing ligand. ML327 blocks MYC expression and tumor formation in neuroblastoma. |
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