CBL0137 hydrochloride
| CAS No. | 1197397-89-9 | Cat. No. | BCP29139 |
| Name | CBL0137 hydrochloride | ||
| Synonyms | CBL-0137;CBL0137; CBL 0137; Curaxin 137;Curaxin-137 hydrochloride; | ||
| Formula | C21H23ClN2O2 | M. Wt | 370.88 |
| Description | CBL0137 activates p53 and inhibits NF-kB with EC50s of 0.37 μM and 0.47 μM in the cell-based p53 and NF-kB reporter assays, respectively. It also inhibits histone chaperone FACT (facilitates chromatin transcription complex). | ||
| Pathways | Apoptosis Pathway NFκB | ||
| Targets | NF κB p53 | ||
Structure
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