CBL0137 hydrochloride
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CAS No. | 1197397-89-9 | Cat. No. | BCP29139 |
Name | CBL0137 hydrochloride | ||
Synonyms | CBL-0137;CBL0137; CBL 0137; Curaxin 137;Curaxin-137 hydrochloride; | ||
SMILES | |||
Chemical Name | |||
Formula | C21H23ClN2O2 | M. Wt | 370.88 |
Purity | 98% | Storage | Store at 4-8°C |
Description | CBL0137 activates p53 and inhibits NF-kB with EC50s of 0.37 μM and 0.47 μM in the cell-based p53 and NF-kB reporter assays, respectively. It also inhibits histone chaperone FACT (facilitates chromatin transcription complex). |
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