Pralsetinib

  • Chemical Properties
CAS No. 2097132-94-8 Cat. No. BCP29411
Name Pralsetinib
Synonyms BLU 667;BLU667;BLU-667;
Formula C27H32FN9O2 M. Wt 533.61
  • Biological Activity
Description Pralsetinib (BLU-667) is a highly potent, selective RET inhibitor. Pralsetinib (BLU-667) inhibits WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion with IC50s of 0.4, 0.3, 0.4, 0.4, and 0.4 nM, respectively.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets RET 

Structure

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