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Pralsetinib Chemical Structure

Pralsetinib

Data Sheet For research use only. Not for human use.
Cat. No. :BCP29411CAS No. :2097132-94-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2097132-94-8 Cat. No. BCP29411
Name Pralsetinib
Synonyms BLU 667;BLU667;BLU-667;
SMILES CC1=CC(=NN1)NC2=NC(=NC(=C2)C)C3CCC(CC3)(C(=O)NC(C)C4=CN=C(C=C4)N5C=C(C=N5)F)OC
Chemical Name
Formula C27H32FN9O2 M. Wt 533.61
Purity 98% Storage Store at 4-8°C
Description Pralsetinib (BLU-667) is a highly potent, selective RET inhibitor. Pralsetinib (BLU-667) inhibits WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion with IC50s of 0.4, 0.3, 0.4, 0.4, and 0.4 nM, respectively.
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