TP0463518
| CAS No. | 1558021-37-6 | Cat. No. | BCP29564 |
| Name | TP0463518 | ||
| Synonyms | TP 0463518；TP-0463518; | ||
| Formula | C20H18ClN3O6 | M. Wt | 431.83 |
| Description | TP0463518 is a novel, highly potent HIF prolyl hydroxylase (PHD) inhibitor with IC50 of 13 nM and 18 nM for human and rat PHD2, respectively; demonstrates to promote the production of erythropoietin (EPO) following oral administration in mice and rats, shows potential for treatment of renal anemia. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | HIF | ||
Structure
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