TP0463518
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1558021-37-6 | Cat. No. | BCP29564 |
| Name | TP0463518 | ||
| Synonyms | TP 0463518；TP-0463518; | ||
| SMILES | ClC(C=C1)=CC=C1OC2=NC=C(CN3C(C(C(NCC(O)=O)=O)=C(O)CC3)=O)C=C2 | ||
| Chemical Name | |||
| Formula | C20H18ClN3O6 | M. Wt | 431.83 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | TP0463518 is a novel, highly potent HIF prolyl hydroxylase (PHD) inhibitor with IC50 of 13 nM and 18 nM for human and rat PHD2, respectively; demonstrates to promote the production of erythropoietin (EPO) following oral administration in mice and rats, shows potential for treatment of renal anemia. | ||
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