Inarigivir
CAS号 | 475650-36-3 | 货号 | BCP29769 |
中文名 | Inarigivir | ||
英文名 | Inarigivir | ||
中文别名 | |||
英文别名 | ORI-9020; ORI 9020; ORI9020; SB-40; SB-9000; SB9000;SB 9000; | ||
分子式 | C20H26N7O10PS | 分子量 | 587.50 |
生物活性 | Inarigivir, also known as ORI-9020 and SB-9000, is a novel dinucleotide, evaluated in transgenic mice expressing hepatitis B virus (HBV), significantly reduced liver HBV DNA (P = 0.001). Levels of HBeAg and HBsAg in serum and of HBcAg in liver were not affected by treatment. A minimal effective dosage was determined to be between 1.6 and 0.5 mg/kg of body weight/day, which was similar to that observed for adefovir dipivoxil. | ||
信号通路 | Microbiology/Virology | ||
靶 点 | HBV |
结构式
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