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CAS号 | 475650-36-3 | 货号 | BCP29769 |
中文名 | Inarigivir | ||
英文名 | Inarigivir | ||
中文别名 | |||
英文别名 | ORI-9020; ORI 9020; ORI9020; SB-40; SB-9000; SB9000;SB 9000; | ||
SMILES | COC1C(C(OC1N2C=CC(=O)NC2=O)CO)OP(=S)(O)OCC3C(CC(O3)N4C=NC5=C4N=CN=C5N)O | ||
化学名称 | |||
分子式 | C20H26N7O10PS | 分子量 | 587.50 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Inarigivir, also known as ORI-9020 and SB-9000, is a novel dinucleotide, evaluated in transgenic mice expressing hepatitis B virus (HBV), significantly reduced liver HBV DNA (P = 0.001). Levels of HBeAg and HBsAg in serum and of HBcAg in liver were not affected by treatment. A minimal effective dosage was determined to be between 1.6 and 0.5 mg/kg of body weight/day, which was similar to that observed for adefovir dipivoxil. |
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