TP-3654
| CAS No. | 1361951-15-6 | Cat. No. | BCP30070 |
| Name | TP-3654 | ||
| Synonyms | TP3654; TP 3654; | ||
| Formula | C22H25F3N4O | M. Wt | 418.46 |
| Description | TP-3654 is a Pim-1 and Pim-3 kinase inhibitor potentially for the treatment of prostate cancer, acute myeloid leukemia, multiple sclerosis and psoriasis. TP-3654 displays favorable human ether-à-go-go-related gene and cytochrome P450 inhibition profiles compared with the first-generation PIM inhibitor, SGI-1776, and exhibits oral bioavailability. | ||
| Pathways | Jak/Stat Pathway | ||
| Targets | Pim | ||
Structure
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