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CAS No. | 1361951-15-6 | Cat. No. | BCP30070 |
Name | TP-3654 | ||
Synonyms | TP3654; TP 3654; | ||
SMILES | CC(C)(C1CCC(CC1)NC2=NN3C(=NC=C3C4=CC(=CC=C4)C(F)(F)F)C=C2)O | ||
Chemical Name | |||
Formula | C22H25F3N4O | M. Wt | 418.46 |
Purity | 98% | Storage | Store at 4-8°C |
Description | TP-3654 is a Pim-1 and Pim-3 kinase inhibitor potentially for the treatment of prostate cancer, acute myeloid leukemia, multiple sclerosis and psoriasis. TP-3654 displays favorable human ether-à-go-go-related gene and cytochrome P450 inhibition profiles compared with the first-generation PIM inhibitor, SGI-1776, and exhibits oral bioavailability. |
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