Porcupine-IN-1
| CAS No. | 2036044-77-4 | Cat. No. | BCP30141 |
| Name | Porcupine-IN-1 | ||
| Synonyms | |||
| Formula | C25H19FN4O | M. Wt | 410.45 |
| Description | Porcupine-IN-1 is potent porcupine inhibitor with an IC50 of 0.5±0.2 nM.Porcupine-IN-1 is as potent as the clinical compound LGK974 in a cell based STF reporter gene assay. Porcupine-IN-1 potently inhibits the secretion of Wnt3A, therefore is confirmed to be a porcupine inhibitor. | ||
| Pathways | Wnt/Stem Cell | ||
| Targets | Porcupine | ||
Structure
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