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CAS No. | 2036044-77-4 | Cat. No. | BCP30141 |
Name | Porcupine-IN-1 | ||
Synonyms | |||
SMILES | CC1=NC=CC(=C1)C2=C(C=C(C=N2)CNC(=O)C3=CC4=C(C=C3)C5=CC=CC=C5N4)F | ||
Chemical Name | |||
Formula | C25H19FN4O | M. Wt | 410.45 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Porcupine-IN-1 is potent porcupine inhibitor with an IC50 of 0.5±0.2 nM.Porcupine-IN-1 is as potent as the clinical compound LGK974 in a cell based STF reporter gene assay. Porcupine-IN-1 potently inhibits the secretion of Wnt3A, therefore is confirmed to be a porcupine inhibitor. |
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