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Porcupine-IN-1 Chemical Structure

Porcupine-IN-1

Data Sheet For research use only. Not for human use.
Cat. No. :BCP30141CAS No. :2036044-77-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2036044-77-4 Cat. No. BCP30141
Name Porcupine-IN-1
Synonyms
SMILES CC1=NC=CC(=C1)C2=C(C=C(C=N2)CNC(=O)C3=CC4=C(C=C3)C5=CC=CC=C5N4)F
Chemical Name
Formula C25H19FN4O M. Wt 410.45
Purity 98% Storage Store at 4-8°C
Description Porcupine-IN-1 is potent porcupine inhibitor with an IC50 of 0.5±0.2 nM.Porcupine-IN-1 is as potent as the clinical compound LGK974 in a cell based STF reporter gene assay. Porcupine-IN-1 potently inhibits the secretion of Wnt3A, therefore is confirmed to be a porcupine inhibitor.
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