PK11007
| CAS No. | 38275-34-2 | Cat. No. | BCP30143 |
| Name | PK11007 | ||
| Synonyms | PK-11007; PK 11007; | ||
| Formula | C6H5ClN2O4S | M. Wt | 236.62 |
| Description | PK11007 is an anti-p53 drug. PK11007 stabilizes wild type and mutant p53 through selective alkylation of two surface cysteines without interfering with its DNA binding. PK11007 preferentially decreases viability in p53-compromised cancer cell lines. IC50 values for inhibition of proliferation in a panel of 17 breast cell lines by PK11007 ranged from 2.3 to 42.2 μM. | ||
| Pathways | Apoptosis Pathway | ||
| Targets | p53 | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.