Lumicitabine
| CAS No. | 1445385-02-3 | Cat. No. | BCP30568 |
| Name | Lumicitabine | ||
| Synonyms | ALS-8176; ALS8176;ALS 8176; JNJ 64041575; JNJ64041575; JNJ-64041575; AL 8176; AL8176; AL-8176; ALS 008176; ALS 008176; ALS008176; | ||
| Formula | C18H25ClFN3O6 | M. Wt | 433.86 |
| Description | Lumicitabine, also known as ALS-8176, is an orally bioavailable prodrug of the novel RSV replication inhibitor ALS-8112. In nonclinical studies, ALS-008112 enters various types of epithelial cells in the respiratory tract and is subsequently phosphorylated to form an intracellular nucleoside triphosphate with a half-life of approximately 29 hours. The nucleoside triphosphate analogue inhibits RSV replication by means of chain termination. | ||
| Pathways | Microbiology/Virology | ||
| Targets | RSV | ||
Structure
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