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Lumicitabine Chemical Structure

Lumicitabine

Data Sheet For research use only. Not for human use.
Cat. No. :BCP30568CAS No. :1445385-02-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1445385-02-3 Cat. No. BCP30568
Name Lumicitabine
Synonyms ALS-8176; ALS8176;ALS 8176; JNJ 64041575; JNJ64041575; JNJ-64041575; AL 8176; AL8176; AL-8176; ALS 008176; ALS 008176; ALS008176;
SMILES CC(C)C(=O)OCC1(C(C(C(O1)N2C=CC(=NC2=O)N)F)OC(=O)C(C)C)CCl
Chemical Name
Formula C18H25ClFN3O6 M. Wt 433.86
Purity 98% Storage Store at 4-8°C
Description Lumicitabine, also known as ALS-8176, is an orally bioavailable prodrug of the novel RSV replication inhibitor ALS-8112. In nonclinical studies, ALS-008112 enters various types of epithelial cells in the respiratory tract and is subsequently phosphorylated to form an intracellular nucleoside triphosphate with a half-life of approximately 29 hours. The nucleoside triphosphate analogue inhibits RSV replication by means of chain termination.
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