FT113

  • Chemical Properties
CAS No. FT113 Cat. No. BCP30637
Name FT113
Synonyms FT-113;FT 113;
Formula C22H20FN3O4 M. Wt 409.42
  • Biological Activity
Description FT113 is a potent and orally active fatty acid synthase (FASN) inhibitor, with an IC50 of 213 nM for full-length recombinant human FASN enzyme. In cell-based assay, FT113 blocks FASN activity in BT474 cells (IC50, 90 nM). FT113 shows anti-proliferative activity, and exhibits anti-cancer both in vitro and in vivo.
Pathways Protease/Metabolic Enzyme 
Targets FAS 

Structure

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