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CAS No. | FT113 | Cat. No. | BCP30637 |
Name | FT113 | ||
Synonyms | FT-113;FT 113; | ||
SMILES | C1CC1(C(=O)N2CCN(CC2)C(=O)C3=CC=C(C=C3)C4=NC5=C(O4)C=C(C=C5)F)O | ||
Chemical Name | |||
Formula | C22H20FN3O4 | M. Wt | 409.42 |
Purity | 98% | Storage | Store at 4-8°C |
Description | FT113 is a potent and orally active fatty acid synthase (FASN) inhibitor, with an IC50 of 213 nM for full-length recombinant human FASN enzyme. In cell-based assay, FT113 blocks FASN activity in BT474 cells (IC50, 90 nM). FT113 shows anti-proliferative activity, and exhibits anti-cancer both in vitro and in vivo. |
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