BMS-1166
| CAS No. | 1818314-88-3 | Cat. No. | BCP30748 |
| Name | BMS-1166 | ||
| Synonyms | BMS 1166;BMS1166;PD-1-IN1;PD-L1-IN1; | ||
| Formula | C36H33ClN2O7 | M. Wt | 641.11 |
| Description | BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM.In Vitro BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 1.4 nM in a homogenous time-resolved fluorescence binding assay. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation. BMS-1166 dose dependently abolishes the inhibition of ECs stimulation by sPD-L1. | ||
| Pathways | Apoptosis Pathway | ||
| Targets | PD 1/PD L1 | ||
Structure
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