BMS-1166 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1818314-88-3 | Cat. No. | BCP30748 |
| Name | BMS-1166 | ||
| Synonyms | BMS 1166;BMS1166;PD-1-IN1;PD-L1-IN1; | ||
| SMILES | CC1=C(C=CC=C1COC2=C(C=C(C(=C2)OCC3=CC=CC(=C3)C#N)CN4CC(CC4C(=O)O)O)Cl)C5=CC6=C(C=C5)OCCO6 | ||
| Chemical Name | |||
| Formula | C36H33ClN2O7 | M. Wt | 641.11 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM.In Vitro BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 1.4 nM in a homogenous time-resolved fluorescence binding assay. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation. BMS-1166 dose dependently abolishes the inhibition of ECs stimulation by sPD-L1. | ||
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