Cintirorgon sodium

  • Chemical Properties
CAS No. 2055538-47-9 Cat. No. BCP30762
Name Cintirorgon sodium
Synonyms LYC-55716 sodium; LYC 55716 sodium; LYC55716 sodium;UNII-T6S6P87405;
Formula C27H22F6NNaO6S M. Wt 625.51
  • Biological Activity
Description Cintirorgon, also known as LYC-55716, is a potent and orally active RORgamma agonist with potential immunomodulatory and antineoplastic activities. LYC-55716 selectively binds to the nuclear receptor transcription factor RORg, forming a receptor complex that translocates to the nucleus, and binds to ROR response elements (ROREs), enhancing the function, proliferation and survival of type 17 T cells, including Th17 (helper T cells) and Tc17 (cytotoxic T cells).
Related Products 2055536-64-4(Cintirorgon)
Pathways Protease/Metabolic Enzyme 
Targets ROR 

Structure

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