Cintirorgon sodium New
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CAS No. | 2055538-47-9 | Cat. No. | BCP30762 |
Related Products | 2055536-64-4(Cintirorgon) | ||
Name | Cintirorgon sodium | ||
Synonyms | LYC-55716 sodium; LYC 55716 sodium; LYC55716 sodium;UNII-T6S6P87405; | ||
SMILES | CC(C)(CC1CN(C2=C(O1)C=CC(=C2)C3=CC(=CC(=C3)F)OC(F)F)S(=O)(=O)C4=CC=CC(=C4)C(F)(F)F)C(=O)[O-].[Na+] | ||
Chemical Name | |||
Formula | C27H22F6NNaO6S | M. Wt | 625.51 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Cintirorgon, also known as LYC-55716, is a potent and orally active RORgamma agonist with potential immunomodulatory and antineoplastic activities. LYC-55716 selectively binds to the nuclear receptor transcription factor RORg, forming a receptor complex that translocates to the nucleus, and binds to ROR response elements (ROREs), enhancing the function, proliferation and survival of type 17 T cells, including Th17 (helper T cells) and Tc17 (cytotoxic T cells). |
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