DMX-5084

  • Chemical Properties
CAS No. 2306178-56-1 Cat. No. BCP30841
Name DMX-5084
Synonyms DMX 5084;DMX5084;
Formula C21H19N3O3 M. Wt 361.39
  • Biological Activity
Description DMX-5804 is a potent, orally active and selective MAP4K4 inhibitor, with an IC50 of 3 nM, a pIC50 of 8.55 for human MAP4K4, less potent on MINK1/MAP4K6 (pIC50, 8.18), and TNIK/MAP4K7 (pIC50, 7.96). DMX-5804 enhances cardiomyocyte survival, and reduces ischemia-reperfusion injury in mice.
Pathways MAPK Pathway 
Targets MAP4K 

Structure

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