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DMX-5084 Chemical Structure

DMX-5084

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP30841CAS No. ：2306178-56-1Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 2306178-56-1 Cat. No. BCP30841
Name DMX-5084
Synonyms DMX 5084；DMX5084;
SMILES O=C1NC=NC2=C1C(C3=CC=C(OCCOC)C=C3)=CN2C4=CC=CC=C4
Chemical Name
Formula C21H19N3O3 M. Wt 361.39
Purity 98% Storage Store at 4-8°C
Description DMX-5804 is a potent, orally active and selective MAP4K4 inhibitor, with an IC50 of 3 nM, a pIC50 of 8.55 for human MAP4K4, less potent on MINK1/MAP4K6 (pIC50, 8.18), and TNIK/MAP4K7 (pIC50, 7.96). DMX-5804 enhances cardiomyocyte survival, and reduces ischemia-reperfusion injury in mice.
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