JNJ-10229570
CAS No. | 524923-88-4 | Cat. No. | BCP30848 |
Name | JNJ-10229570 | ||
Synonyms | JNJ10229570; JNJ 10229570; | ||
Formula | C22H19N3O2S | M. Wt | 389.47 |
Description | JNJ-10229570 is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the production of sebum-specific lipids. JNJ-10229570 inhibits the binding of 125I-NDP-α-MSH to cells expressing human MC1R and MC5R, with IC50 values of 270 nM and 200 nM, respectively. | ||
Pathways | GPCR/G Protein | ||
Targets | Melanocortin Receptor |
Structure
![](https://img.biochemsafebuy.com/uploads/company8/20190625/1561434467_hxlmf.gif)
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