JNJ-10229570 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 524923-88-4 | Cat. No. | BCP30848 |
| Name | JNJ-10229570 | ||
| Synonyms | JNJ10229570; JNJ 10229570; | ||
| SMILES | COC1=CC=CC=C1C2=NC(=NC3=CC=CC=C3)SN2C4=CC=CC=C4OC | ||
| Chemical Name | |||
| Formula | C22H19N3O2S | M. Wt | 389.47 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | JNJ-10229570 is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the production of sebum-specific lipids. JNJ-10229570 inhibits the binding of 125I-NDP-α-MSH to cells expressing human MC1R and MC5R, with IC50 values of 270 nM and 200 nM, respectively. | ||
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