ETC-206
| CAS No. | 1464151-33-4 | Cat. No. | BCP30906 |
| Name | ETC-206 | ||
| Synonyms | ETC 206; ETC206;ETC-1907206; | ||
| Formula | C25H20N4O2 | M. Wt | 408.46 |
| Description | ETC-206 is a selective MNK1/2 inhibitor with IC50 = 64 nM (for MNK1) and IC50 = 84 nM (for MNK2). ETC-206 in combination with dasatinib prevents BC-CML LSC self-renewal in vitro and enhances dasatinib antitumor activity in vivo. | ||
| Pathways | MAPK Pathway | ||
| Targets | MNK | ||
Structure
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