Brevilin A
| CAS No. | 16503-32-5 | Cat. No. | BCP30982 |
| Name | Brevilin A | ||
| Synonyms | Brevilin-A; 6-OAP; 6-O-Angeloylplenolin; 6OAngeloylplenolin; | ||
| Formula | C20H26O5 | M. Wt | 346.43 |
| Description | Brevilin A, also called 6-O-Angeloylplenolina, is a natural sesquiterpenoid found in the herbs of Centipeda minima, it exhibits the antigiardial activity (IC50 = 16.1 μM) and is similarly active in vitro against Entamoeba histolytica (IC50 between 4.5 and 9 μM) and against Plasmodium falciparum (IC50 = 9.42 μM). Brevilin A inhibits janus kinase activity and exhibits both strong STAT3 signal inhibition and STAT3 signal dependent cell growth inhibition. | ||
| Pathways | Jak/Stat Pathway Wnt/Stem Cell | ||
| Targets | Stat | ||
Structure
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