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Brevilin A Chemical Structure

Brevilin A

Data Sheet For research use only. Not for human use.
Cat. No. :BCP30982CAS No. :16503-32-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 16503-32-5 Cat. No. BCP30982
Name Brevilin A
Synonyms Brevilin-A; 6-OAP; 6-O-Angeloylplenolin; 6OAngeloylplenolin;
SMILES CC=C(C)C(=O)OC1C2C(C(=O)OC2CC(C3C1(C(=O)C=C3)C)C)C
Chemical Name
Formula C20H26O5 M. Wt 346.43
Purity 98% Storage Store at 4-8°C
Description Brevilin A, also called 6-O-Angeloylplenolina, is a natural sesquiterpenoid found in the herbs of Centipeda minima, it exhibits the antigiardial activity (IC50 = 16.1 μM) and is similarly active in vitro against Entamoeba histolytica (IC50 between 4.5 and 9 μM) and against Plasmodium falciparum (IC50 = 9.42 μM). Brevilin A inhibits janus kinase activity and exhibits both strong STAT3 signal inhibition and STAT3 signal dependent cell growth inhibition.
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